[Biochemical parameters in the blood in patients during open-heart surgery. II. Malondialdehyde, superoxide dismutase and catalase as indicators of formation and elimination of free oxygen radicals].

Investigation of cardiosurgical patients have provided evidence for the generation of free oxygen radicals during open heart surgery. The finding of increased plasma malondialdehyde concentrations, considered to be an indicator of lipid peroxidation in cell membranes, is suggestive of this process. Simultaneously, the antiradical capacity of tissue was found to exhibit a decreasing trend, as established by the levels of superoxide dismutase and catalase in erythrocytes of peripheral blood which tended to diminish.

Protective effect of alpha-tocopherol and L-ascorbic acid against the ischemic-reperfusion injury in patients during open-heart surgery.

The purpose of the investigation was: 1. to examine the effect of cardiopulmonary bypass (CPB) on the generation of cytotoxic oxygen-derived radicals and 2. to determine if the pretreatment of patients with vitamins E and C will combat generation of such radicals.

[Atherogenicity indices and coronary risk].

The authors compared three different indices, of atherogenicity in 120 men with ischaemic heart disease, type stable angina pectoris (mean age 35.9 +/- 7.54 years) with 30 men of a control group--mean age 42.

[Relative mass and serum lipids in men with various coronary scores].

The authors evaluated the relationship between relative body weight according to Broca and serum lipids in 120 men with stable angina pectoris with a positive coronary score and in 30 men with cardiovertebrogenic syndrome and a negative coronary score. The differences between the Broca index and serum lipid values between men with angina and men of the control group were statistically significant (p less than 0.001); the differences were independent on the value of Broca's index.

[Hyperlipoproteinemia, risk indicators and ischemic heart disease].

The authors analyzed the incidence of risk indicators in a group of 120 men with ischaemic heart disease, type stable angina pectoris, with a positive coronary score in a group of 30 men with a negative coronary score. The mean age of the probands was 35 +/- 7.539 years, in men of the control group 42.