Publications by authors named "O Liew"
In gel electrophoresis, samples that are dispensed too high above or too low into the wells result in sub-optimal outcomes. Here, an adapted 3D printer liquid handler equipped with an optical sensor was found to attain vertical sample delivery positionings at a standard deviation over mean ratio of 0.008.
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- * Conducted on 122 patients with moderate to severe aortic stenosis, the research identified specific circulating proteins that correlate with higher risks of heart failure, severe symptoms, and mortality.
- * Key proteins linked to inflammation and immune responses were significantly associated with worse outcomes, particularly in patients showing reduced heart strain, suggesting new avenues for assessing patient risk beyond standard imaging methods.
Purpose: To investigate the diversity of ocular manifestations in patients with positive perinuclear antineutrophil cytoplasmic antibody (p-ANCA).
Methods: The clinical records of five patients exhibiting ocular manifestations and testing positive for serum MPO-ANCA were retrospectively reviewed.
Results: Three out of five patients were female.
Aims: The performance of circulating soluble urokinase plasminogen activator receptor (suPAR) for predicting the composite endpoint of subsequent heart failure (HF) hospitalisation and/or death at 1 year was assessed in (i) patients with undifferentiated breathlessness, and generalisability was compared in (ii) disparate Western versus Asian sub-cohorts, and in (iii) the sub-cohort adjudicated with HF.
Methods And Results: Patients with acute breathlessness were recruited from the emergency departments in New Zealand (NZ, n = 612) and Singapore (n = 483). suPAR measured in the presentation samples was higher in patients incurring the endpoint (n = 281) compared with survivors (5.
Article Synopsis
- The study aimed to explore how serial measurements of NT-proBNP, a heart failure biomarker, relate to cardiac changes and patient outcomes, considering various clinical factors.
- Analysis involved 1911 heart failure patients, revealing that NT-proBNP levels generally declined, especially in certain groups like inpatients and those on guideline-recommended medications.
- An increase in NT-proBNP over time was linked to a higher risk of hospitalization or death, with variations noted based on patient age, atrial fibrillation presence, and heart failure types.