Publications by authors named "O L T Lam"
Background: Efficacy of remdesivir for COVID-19 remains unclear. We updated our published systematic review to better inform on the use of remdesivir for COVID-19.
Methods: We searched for randomized controlled trials (RCTs) among hospitalized COVID-19 patients.
Plant trait data are used to quantify how plants respond to environmental factors and can act as indicators of ecosystem function. Measured trait values are influenced by genetics, trade-offs, competition, environmental conditions, and phenology. These interacting effects on traits are poorly characterized across taxa, and for many traits, measurement protocols are not standardized.
View Article and Find Full Text PDFBackground: Aberrant neuronal Sigma-1 receptor (Sig-1r)-mediated endoplasmic reticulum (ER)- mitochondria signaling plays a key role in the neuronal cytopathology of Alzheimer's disease (AD). The natural psychedelic N, N-dimethyltryptamine (DMT) is a Sig-1r agonist that may have the anti-AD potential through protecting neuronal ER-mitochondrial interplay.
Methods: 3×TG-AD transgenic mice were administered with chronic DMT (2 mg/kg) for 3 weeks and then performed water maze test.
Article Synopsis
- The study investigates the oral care knowledge, attitude, and practice (KAP) of nursing staff in acute hospital settings, which is under-researched.
- It utilizes a modified 55-item questionnaire to assess KAP levels among 404 nursing staff, revealing that only about 29.5% had good knowledge, 33.7% had a positive attitude, and 14.9% demonstrated good practice concerning oral care.
- The findings highlight that higher knowledge and favorable attitudes correlate with better oral care practices, emphasizing the need for standardized training and tools to improve oral care delivery in hospitals.
Purpose: This study aimed to assess the effectiveness of ultrasonic denture hygiene interventions in improving denture cleanliness among elderly individuals.
Materials And Methods: Sixty-six participants who had received upper metal framework removable partial dentures within the past 5 years were randomly allocated into three denture hygiene intervention groups: group 1 (mechanical cleaning with a toothbrush and ultrasonic cleaning with cetylpyridinium chloride), group 2 (mechanical cleaning with a toothbrush and ultrasonic cleaning with distilled water), and control (mechanical cleaning with a toothbrush only). Denture cleanliness was assessed at baseline and 1-month using: i) Denture Cleanliness Index (DCI) scores; ii) plaque coverage percentage; and (iii) microbiological samples for bacterial and yeast detection.