Publications by authors named "O L Lyytinen"
Infections caused by multidrug-resistant (MDR) bacteria are a growing global concern. Enterobacter cloacae complex (ECC) species are particularly adept at developing antibiotic resistance. Phage therapy is proposed as an alternative treatment for pathogens that no longer respond to antibiotics.
View Article and Find Full Text PDFMicrobial production of lipid-protein vesicles using enveloped bacteriophage phi6.
Microb Cell Fact
February 2019
Background: Cystoviruses have a phospholipid envelope around their nucleocapsid. Such a feature is unique among bacterial viruses (i.e.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the replication cycle of double-stranded RNA viruses, particularly how the viral RNA-dependent RNA polymerase (RdRP) functions within the viral capsid of the human picobirnavirus (hPBV).
- Researchers determined the structure of the hPBV RdRP, highlighting a unique flexible loop that plays a crucial role in RNA replication.
- The findings indicate that the RdRP is active with both single-stranded and double-stranded RNA, relies on viral RNA for capsid incorporation, and shows a preference for specific RNA sequences during transcription.
Sortase-dependent surface pili (or fimbriae) in Gram-positive bacteria are well documented as a key virulence factor for certain harmful opportunistic pathogens. However, it is only recently known that these multi-subunit protein appendages are also belonging to the "friendly" commensals and now, with this new perspective, they have come to be categorized as a niche-adaptation factor as well. In this regard, it was shown earlier that sortase-assembled piliation is a native fixture of two human intestinal commensalics (i.
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