Publications by authors named "O L Kaplan"
Article Synopsis
- The study aimed to determine how common Retinopathy of Prematurity (ROP) and other eye diseases are in late preterm infants at a hospital in Turkey and whether routine ROP screenings are necessary.
- It included 600 late preterm infants from a neonatal intensive care unit, finding that 3.3% developed ROP and 4.8% had other eye issues, with a significant link between these conditions and lower birth weight and gestational age.
- The researchers concluded that while the incidence of ROP in late preterm infants is low, routine screening is essential to identify and treat ROP and other ocular problems early, preventing serious vision loss.
In this study, we investigated the effect of chitosan modification with tricine on transfection efficiency by preserving its ability to form complexes with plasmid DNA (pDNA) and increasing its hydrophilicity. The inherent limitations of chitosan, such as poor solubility at physiological pH, insufficient cellular uptake, and strong ionic interactions with pDNA, typically result in low transfection efficiency. To overcome these challenges, Tricine, a hydrophilic molecule containing a secondary amine group, was conjugated to chitosan.
View Article and Find Full Text PDFBackground: Since nursing students' interactions with nurses in the clinical practice process play an important role in nursing education and practice, it is a necessity to evaluate nurses' attitudes towards students.
Aim: To develop a valid and reliable measurement tool to determine the attitudes of nurses' towards nursing students in the clinical practice process.
Design: This study used a quantitative cross-sectional design.
Evaluation of Antivenom Therapy for Middle East Scorpion Envenomations.
Pediatr Emerg Care
November 2024
Introduction: Scorpion envenomation is a leading cause of envenomation in our region. Antivenom has been used successfully to treat the systemic manifestations of envenomations inflicted by toxic scorpions. Toxic scorpions common in our area include Leiurus quinquestriatus, Androctonus australis, and Buthus occitanus.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on creating a new amphiphilic chitosan (Chi-MA) by combining myristic acid and tertiary amine groups for better gene delivery.
- The modified chitosan underwent thorough chemical characterization and was used to form nanoparticles, which were tested for their size, stability, and capabilities to deliver genes effectively.
- Results showed that Chi-MA significantly improved gene complexing (8-fold increase) and transfection efficiency without causing toxicity to HEK293T cells, highlighting it as an effective gene carrier.