Publications by authors named "O Klepp"

Background: Selection bias due to non- or incomplete compliance is challenging in surveys. Using data from a longitudinal survey in testicular cancer survivors (TCSs), we identify factors predicting incomplete compliance.

Method: In a questionnaire-based national survey (1998-2016; three waves) 1,813 > 5 year TCSs were invited to report post-treatment adverse health outcomes (AHOs).

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Background: Testicular germ cell tumor (TGCT) patients and survivors have excess mortality compared to the general male population, but relative survival (RS) has been scarcely studied. We investigated causes of excess mortality and their impact on RS among men diagnosed with TGCT in Norway, 1953-2015.

Methods And Findings: Using registry data (n = 9541), standardized mortality ratios (SMRs) and RS were calculated.

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Article Synopsis
  • Curative radiation therapy is essential for prostate cancer treatment, and the study analyzed long-term risks of second cancers (SC) and overall survival (OS) among patients receiving hormone therapy (ET) alone versus combined with radiation (RT).
  • Among the 860 analyzed patients, those receiving combined treatment had a higher incidence of SC, especially urinary bladder cancer (UBC), but improved overall survival rates compared to those on hormone therapy alone.
  • The findings indicate that despite a heightened risk for certain second cancers, the overall survival benefits associated with combined ET and RT therapies significantly outweigh the potential risks.
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The aim of this registry-based cohort study was to estimate second cancer (SC) risk following radical prostate cancer (PC) treatment and evaluate if the risk was influenced by radiotherapy. We collected data from the Cancer Registry of Norway on all patients with PC as first cancer diagnosis, from 1997 to 2014. Standardized incidence ratios (SIRs) for SC were calculated by comparing our cohort to the standard male population.

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