Publications by authors named "O Kepple"

Article Synopsis
  • Ancestral signaling pathways are crucial for development, physiology, and immunity in metazoans, highlighting the importance of interspecies communication.
  • Researchers identified a tick receptor called Dome1 that has evolved to interact with the mammalian cytokine IFN-γ, activating the JAK-STAT pathway, which aids in tick feeding and development.
  • The Dome1-JAK-STAT pathway, present in many Ixodid ticks, influences gut cell regeneration and metamorphosis through interactions with the Hedgehog and Notch-Delta networks, showcasing the evolutionary link between ticks and mammalian hosts.
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The main purpose of veterinary education institutions is to prepare qualified, well-trained and knowledgeable professionals ready to serve local and global communities. Veterinary programmes vary within and among countries, creating a disparity in competencies. In less-developed economies, adhering to the World Organisation for Animal Health (OIE) ‘Day 1 competencies' and following its ‘Guidelines for a Model Core Veterinary Curriculum' may decrease this discrepancy.

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