Exploring factors that impact pass rates in a UK pharmacist registration exam, 2011-2024.

Objectives: The aim of this work was to evaluate the performance of UK MPharm graduates on the General Pharmaceutical Council's (GPhC) registration assessment, between the years 2011-2024, to explore the factors that impact student performance in this examination.

Methods: Student performance in the GPhC registration assessment was contextualized with factors like alma mater, Foundation Training placement, NSS, and HESA data. Relationships between these factors and the weighted average passing rates and raw scores were analysed using a range of statistical methods including correlation analysis, ANOM, Tukey-Kramer, and t-tests.

A randomized crossover design study comparing the pharmacokinetics and pharmacodynamics of 2 single doses of oral aspirin (75 mg v 150 mg) in pregnant women at risk of preeclampsia: implications on assessing aspirin response and patient adherence to therapy.

Background: Pregnancy is associated with physiological changes that can alter the pharmacokinetic and pharmacodynamic profile of many drugs. Low-dose aspirin is used for preeclampsia prevention; however, aspirin's pharmacokinetics and pharmacodynamics are poorly studied in pregnant women.

Objective: The aim of this study was to compare the pharmacodynamics of 2 common doses of aspirin (75 and 150 mg) used for preeclampsia prevention in high-risk women by examining their effect on thromboxane B inhibition.