Effect of acute Trypanosoma vivax infection on cattle erythrocyte glutathione and susceptibility to in vitro peroxidation.

During acute Trypanosoma vivax infection of calves, produced by intravenous inoculation, the mean packed cell volume and red blood cell counts of the infected animals decreased significantly (P < 0.05) between Days 6 and 13 post-infection (pi). The moderately severe normocytic anaemia started to develop during the first wave of parasitaemia which occurred from Day 2 pi and peaked between Days 4 and 5 pi.

Increased susceptibility of erythrocytes to in vitro peroxidation in acute Trypanosoma brucei infection of mice.

Trypanosoma brucei, Wamba strain, produced an acute infection in mice, and mortality was observed 2 days after the onset of parasitaemia which occurred 3-5 days postinfection. Anaemia was observed in the tail blood of the survivors. When washed erythrocytes from the heart blood were incubated in physiological saline containing 1.