Publications by authors named "O K Kulchitsky"

Article Synopsis
  • The study focuses on internal hernias in young children, particularly those strangulated in mesenteric openings, examining symptoms, diagnosis, and treatment methods.
  • Five children under three years old were analyzed, with cases involving small intestine infringements and varying outcomes based on whether they received timely surgical care.
  • The findings highlight the challenges in diagnosing these internal hernias due to non-specific symptoms, emphasizing that early diagnosis and prompt surgery are crucial for better prognosis.
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Aim: To analyze the clinical spectrum of urogenital tuberculosis (TB) in children from 1993-1997 to 2013-2017, who were treated at the FSCU "Kiritsy".

Materials And Methods: Clinical forms of urogenital tuberculosis were diagnosed in 195 children (stage 1) and 158 children (stage 2). Conventional methods of TB diagnosis, including clinical, laboratory, imaging studies, tuberculin skin test and urine culture for BCG were used.

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Transfer of human apoAI gene, within the molecular construction which provides its expression, to the liver of adult and aged rats resulted in the appearance of human protein in their blood, and was accompanied by changes in the content of high-density lipoproteins, as well as by the shifts in their protein and lipid composition. Administration of the human ApoAI gene was followed by changes of the vasoactive effects of HDL. Gene implantation is capable of enhancing the direct vasodilatory effects of HDL in old animals, being weakened by ageing, even against the background of normal age changes in the vascular wall tone.

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Article Synopsis
  • - Experiments on both adult and old rats showed that blood lipoproteins have a dilating effect on the thoracic aorta, but this effect decreases with age.
  • - Older rats exhibited lower sensitivity in their blood vessels to all lipoprotein fractions compared to younger rats, particularly noting HDL's reduced ability to cause vasodilation with age.
  • - Changes in HDL composition with age included a decrease in phospholipids and an increase in total cholesterol, while the vasodilatory effects of LDL and VLDL remained constant.
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Effect of insulin on Na, K-ATPase activity and phospholipid (PL) composition of myocardiocytes' plasma membrane (PM) was investigated in adult (6 months old) and old (28 months old) male Wistar rats. Administration of insulin increases Na, K-ATPase activity and phosphatidilethanolamin content, and decreases phosphatidilinositol content of myocardiocytes' PM in adult animals. Administration of insulin doesn't change Na, K-ATPase activity and decreases phosphatidilethanolamin content of myocardiocytes' PM in old rats.

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