Publications by authors named "O J Simon"

Background And Aims: LGBTQIA2S + populations are believed to be at higher risk of problem gambling due to their elevated rates of mental disorders and substance abuse compared to heterosexual and cisgender populations. However, little is known about these populations regarding their gambling practices in the Canadian context.

Methods: We conducted an online survey among Canadian residents 18 years or older who self-identify as sexually and gender-diverse (i.

View Article and Find Full Text PDF

Background: Although the benefit of supportive care in the postcancer period is now well demonstrated, its implementation in the patient journey remains challenging. This article describes the development, since 2015 and in routine care, of supportive postcancer care comprising a multidisciplinary rehabilitation programme (MRP) based on exercise for patients with early breast cancer.

Methods: As part of quality control, we reviewed all patient files since the programme was implemented.

View Article and Find Full Text PDF

Patients with gastrointestinal bleeding (GIB) exhibit varying tolerances to acute blood loss. We aimed to investigate the effect of relative Hb decrease (ΔHb%) on GIB outcomes. Participants enrolled in the Hungarian GIB Registry between 2019 and 2022 were analyzed.

View Article and Find Full Text PDF

This case series describes the clinical features, diagnostic challenges, treatment approaches, and outcomes of three adult patients with COQ8A-related CoQ10 deficiency presenting with focal status epilepticus, who were effectively treated at the Department of Neurology, Philipps University Marburg, Marburg, Germany. The patients, all from consanguineous families with the first two being siblings, presented with a late onset of the disease, characterized by progressive cerebellar ataxia and epilepsy, with clinical deterioration and focal status epilepticus occurring in adulthood. The first patient exhibited myoclonic status, while the second and third patients presented with bilateral tonic-clonic seizures followed by focal status epilepticus manifesting with cortical blindness.

View Article and Find Full Text PDF
Article Synopsis
  • Elevated lipoprotein(a) [Lp(a)] is linked to increased risk of ischaemic heart disease (IHD), and the study aimed to analyze IHD patients with Lp(a) measurements, focusing on the connection between elevated Lp(a) levels and premature IHD.
  • A retrospective study of 521 IHD patients in Singapore revealed that 10% experienced premature IHD, with most having normal Lp(a) levels, though Indian ethnicity and female patients showed higher concentrations.
  • Findings suggested that Lp(a) levels ≥155 mmol/L significantly correlate with the development of premature IHD, highlighting the influence of ethnicity and gender on Lp(a) distribution.
View Article and Find Full Text PDF