[Complex treatment for decompensated edematous exophthalmos].

In endocrine ophthalmolopathy, there may be persistent dysfunction of the organ of vision due to corneal lesion or optical neuropathy. As an illustration of severe corneal lesion in edematous exophthalmos decompensation, the authors give their own observation that shows it necessary to use in such cases complex treatment comprising pulse therapy with glucocorticoids, followed by a long-term dosage reduction and switching over to its oral administration, as well radiotherapy and surgery.

[Analysis of changes in the accumulation of the photosensitizer Photosens, its elimination kinetics and distribution in the tissues of the eye and eyelids in health and in some tumorous processes].

The authors analyze and present the results of spectroscopic studies into changes in the accumulation of the photosensitizer Photosens, its elimination kinetics and distribution in the tissues of the eye and eyelids, as well as in the tumors that have developed at these sites. The findings allowed the authors to estimate the duration of the agent's persistence in the eye tissues and the time interval associated with the high risk for phototoxic eyelid skin and conjunctival reactions and to determine a possibility of and conditions for photodynamic therapy, as well as the length of hospital stay when the latter was performed.

[Experimental rationale for a transscleral approach to thermotherapy for intraocular tumors, by using a photosensitizer].

The authors present the results of an experimental study of the pattern of distribution of laser radiation at a wavelength of 810 nm in the normal and Photosens-photosensitized eye tissues and analyze the distribution of a temperature at the sclera/choroidea/ tumor border during transscleral radiation delivery. To further the goal, the authors have resorted to computer mathematical simulation. In convergent-beam radiation supply, the proportion of a scattered radiation component has been ascertained to be lower in the surface scleral layer than that in the layers adjacent to the choroidea and the base of a tumor.