Publications by authors named "O Iu Ioffe"
Objective: Aim: To study the impact of bariatric interventions on changes in the parameters of the intestinal microbiome.
Patients And Methods: Materials and Methods: The research method is a prospective observational cohort monocentric study. 112 patients were included in the study.
Objective: Aim: To study the effectiveness of BTA in a total dose of 100 IU as the preparation for patients with primary and incisional ventral hernias (VH).
Patients And Methods: Materials and Methods: The prospective study included 59 patients with large VH (defect ³10 cm). All patients received 100 IU of BTA in abdominal wall muscles 4-5 weeks before surgery from June 2017 to December 2022.
Article Synopsis
- The study aimed to enhance the management of morbidly obese patients undergoing gastric bypass to decrease postoperative complications, especially bleeding.
- It involved 348 patients treated between 2011 and 2022, comparing outcomes from a retrospective group (178 patients) and a prospective group (170 patients).
- Results showed a significant reduction in postoperative bleeding from 4.49% in the retrospective group to 1.76% in the prospective group, with identified risk factors including comorbid conditions and chronic diseases, leading to a new postoperative management strategy.
Diabetes commonly affects patients with cancer. We investigated the influence of diabetes on breast cancer biology using a 3-pronged approach that included analysis of orthotopic human tumor xenografts, patient tumors, and breast cancer cells exposed to diabetes/hyperglycemia-like conditions. We aimed to identify shared phenotypes and molecular signatures by investigating the metabolome, transcriptome, and tumor mutational burden.
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