Copy number variations of stepwise-selected doxorubicin-resistant MCF-7 cell lines.

Elimination of cytotoxic effect in cells with multidrug resistance (MDR) phenotype is a situation that is gradually acquired over time and develops through multiple pathways resulting in global phenotypic changes of cells. Although molecular background of the resistance phenotype has widely been studied in the gene expression level, segmental and gene copy number variations (CNVs) have limitedly been documented. Thus, in the present study, we aimed to analyze the CNVs using DNA microarray in the sensitive and two doxorubicin-resistant MCF-7 breast cancer cell lines which had different resistance indices.

The relationship between the frequency of use of non-medication coping strategies with urinary incontinence and depression in older adults.

Background: The aim of this study is to examine the relationship between the frequency of use of non-medication coping strategies with urinary incontinence (UI) and depression in older adults.

Methods: This study followed a descriptive design and was conducted with 345 older adults over the age of 65. The data of the study were collected using the Geriatric Depression Scale Short Form and the Frequency of Non-Medication Coping Strategies with Urinary Incontinence Scale.

Effect of environmental education program implemented with university student participation on secondary school students' environmental attitude.

Study aimed to increase university students' sensitivity and the environmental attitudes of secondary school students through environmental education program. It was planned as quasi-experimental research. The first phase was completed with five fourth-year students who took Social Awareness Course at a university's nursing department in Turkey.

The influence of the online education provided using the six thinking hat method on the knowledge and attitudes of nursing students regarding pressure injury prevention; a pilot study.

Aim: The study aims to investigate the influence of the online education given to nursing undergraduate students using the Six Thinking Hat Method (STHM) on their knowledge and attitudes related to pressure injury (PI) prevention.

Methods: This pilot study was conducted between March-June 2023. The research sample consists of 25 participants in the intervention group and 25 in the control group.

The Effect of Acceptance and Commitment Therapy-Based Psychoeducation on Body Image, Quality of Sexual Life, and Dyadic Adjustment of Women After Breast Cancer Surgery.

Objectives: To determine the effect of acceptance and commitment therapy-based psychoeducation applied to women who have undergone breast cancer surgery on body image, quality of sexual life, and dyadic adjustment.

Sample & Setting: Women who have undergone breast cancer surgery were included. The research had a single-group quasi-experimental design with pre-/post-test measurements and 31 participants.