Publications by authors named "O Ia Potapenko"
Article Synopsis
- Metformin, a diabetes medication, appears to offer cardiovascular protection and influences gut microbiota in hypertensive rats.
- In the study, metformin treatment increased short-chain fatty acids (SCFAs) in feces, lowered blood pressure, and improved cardiac function, despite some increase in cardiac hypertrophy.
- The research suggests that SCFA levels may mediate the observed anti-inflammatory and blood pressure-lowering effects of metformin, even in the absence of diabetes.
Objective: The aim: To evaluate and compare the prevalence of gingivitis according to the PMA index in children aged 5 to 6 years in preschool with ASD and without disorders (Kyiv, Ukraine).
Patients And Methods: Materials and methods: Oral assessment was conduct on 69 children with ASD and 23 children without ASD aged 5 to 6 years. To determine the periodontal status it was used the papillary-marginal-alveolar index - PMA (according to Schour, Massler, in the modification of Parma).
Background: Peanut allergy is a frequent cause of food allergy and potentially life-threatening. Within this interdisciplinary research approach, we aim to unravel the complex mechanisms of peanut allergy. As a first step were applied in an exploratory manner the analysis of peanut allergic versus non-allergic controls.
View Article and Find Full Text PDFRationale: Antibiotic treatment of patients infected with G(-) or G(+) bacteria promotes release of the toxins lipopolysaccharide (LPS) and pneumolysin (PLY) in their lungs. Growth Hormone-releasing Hormone (GHRH) agonist JI-34 protects human lung microvascular endothelial cells (HL-MVEC), expressing splice variant 1 (SV-1) of the receptor, from PLY-induced barrier dysfunction. We investigated whether JI-34 also blunts LPS-induced hyperpermeability.
View Article and Find Full Text PDFThe authors' studies have established that the concentration of Rickettsia typhi may increase about 100-fold in the infected Ornithonyssus bacoti mites. At the time, when on feeding 20 to 200 adult mites on guinea-pigs and albino rats 4 to 36 days after inoculation, they did not transmit Rickettsia typhi on blood sucking.
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