Publications by authors named "O I Zaĭtsev"
[Neuromodulatory pharmacotherapy individualization in prolonged and chronic consciousness disorders after severe traumatic brain injury].
Zh Vopr Neirokhir Im N N Burdenko
June 2024
One of the most probable causes of effective therapy for post-comatose disorders of consciousness is the lack of individualization of drug prescriptions. In this observational study, we analyzed 48 courses of neuromodulatory therapy in 28 patients with prolonged and chronic disorders of consciousness following severe traumatic brain injury. Comparison of 24 effective and 24 ineffective courses demonstrated higher effectiveness of pharmacotherapy through its individualization, i.
View Article and Find Full Text PDFObjective: To analyze modern literature data on biochemical markers of critical mesenteric ischemia.
Material And Methods: We analyzed the most promising, highly specific and sensitive biochemical markers of total and segmental intestinal damage following acute mesenteric ischemia. Analysis included domestic and foreign literature data between 2015 and 2023.
The objective of the present study was to review recent epidemiological and clinical data on the association between selected minerals and trace elements and osteoporosis, as well as to discuss the molecular mechanisms underlying these associations. We have performed a search in the PubMed-Medline and Google Scholar databases using the MeSH terms "osteoporosis", "osteogenesis", "osteoblast", "osteoclast", and "osteocyte" in association with the names of particular trace elements and minerals through 21 March 2023. The data demonstrate that physiological and nutritional levels of trace elements and minerals promote osteogenic differentiation through the up-regulation of BMP-2 and Wnt/β-catenin signaling, as well as other pathways.
View Article and Find Full Text PDFIntroduction: At present, selective amygdalohippocampectomy (SAH) has become popular in the treatment of drug-resistant mesial temporal lobe epilepsy (TLE). However, there is still an ongoing discussion about the advantages and disadvantages of this approach.
Methods: The study included a consecutive series of 43 adult patients with drug-resistant TLE, involving 24 women and 19 men (1.
Article Synopsis
- Tourette syndrome (TS) is a complex disorder characterized by motor and vocal tics, often alongside psychiatric issues like OCD, ADHD, depression, and anxiety.
- Treatment typically involves non-drug methods such as therapy and relaxation techniques, while severe cases may consider pharmacotherapy or neurosurgical options like deep brain stimulation (DBS).
- Current research on DBS shows promise for drug-resistant TS cases, but challenges remain regarding patient selection and ethical considerations, as most studies involve only a small number of patients.