Publications by authors named "O I Urazova"
Article Synopsis
- * Anthracyclines, particularly doxorubicin, are effective in fighting tumors but can cause serious heart damage, known as cardiotoxicity.
- * Understanding how doxorubicin affects heart function is essential for creating new protective strategies against its harmful impacts on the cardiovascular system.
Rheumatoid arthritis (RA) is an idiopathic, autoimmune connective tissue disorder that primarily affects the synovial joints, causing symmetric, erosive-deforming polyarthritis. It is also associated with extra-articular manifestations, particularly cardiovascular (CV) diseases (CVD). CV risk modification in RA remains unsolved despite recent advances in the management of RA.
View Article and Find Full Text PDFDiabetes mellitus (DM) is considered by many the pandemic of the 21st century and is associated with multiple organ damages. Among these, cardiovascular complications are responsible for an incredible burden of mortality and morbidity in Western Countries. The study of the pathological mechanisms responsible for the cardiovascular complications in DM patients is key for the development of new therapeutic strategies.
View Article and Find Full Text PDFBackground: The angiopoietic endothelial dysfunction in ischemic cardiomyopathy (ICMP) remains unexplored.
Aim: The identification of the imbalance of endothelial dysfunction mediators and the number of endothelial progenitor (EPC) and desquamated (EDC) cells in patients with coronary heart disease (CHD) with and without ICMP.
Methods: A total of 87 patients (47 with ICMP and 40 without ICMP) were observed.