[Treatment of purulent wounds by using of negative pressure].

It was analyzed the results of wounds treatment complicated by surgical infection. An apparatus for creating negative pressure VivanoTec/S042 was used for this in 74 patients. Types of surgical interventions depended on phase of inflammatory process and severity of clinical manifestations.

[Biocomposite nanostructured materials for the bone defects filling by osteomyelitis].

Results of the use of the biocomposite nanostructured material "KollapAn" in the treatment of 374 patients with osteomyelitis were followed up. 412 operations were performed, depending on the stage of the inflammatory process and clinical picture. Majorly, operation was performed on the 5-7th day after primary necrosequestrectomy.

[Clinico-morphological aspects of diagnostics and treatment of the surgical sepsis].

Treatment results of 63 patients with surgical sepsis (aged 17-92 years) were analyzed. The necessity of intravenous immunoglobulin infusion in the complex treatment of sepsis was proved by the comparative morphological study of immunocompetent tissues of 30 patients, died of sepsis and nonseptic reasons. The rational use of intravenous immunoglobulin should be based on the condition of the patient and defined by the APACHE II and SOFA scores.

[Immunotherapy in complex treatment of surgical sepsis].

The results of treatment of 73 patients with confirmed diagnosis of sepsis are analyzed. The most frequent immune disorders in septic patients are: decrease in lymphocyte count, both T (60%) and B (45.7%) populations, decrease of T-helpers and T-suppressors (52.