[Factors influencing ocular angiogenesis].

The review of literature covers the topical aspects of the interaction of proangiogenic cytokines and angiogenic inhibitors, their implication in the pathogenesis of proliferative retinopathies occurring, among other diseases, in the presence of diabetes mellitus. The paper provides the historical facts of development of the angiogenic homeostasis theory that implies that there is a dynamic equilibrium between two antagonistic systems: proangiogenic and antiangiogenic. The major angiogenic inhibitors involved in the maintenance of the normal structure and function of the eye and in the processes linked with abnormal proliferation are enumerated.

[Electroretinography in regmatogenic retinal detachment in the myopic eye].

The investigation studied the topographic features of retinal electrogenesis in regmatogenic retinal detachment (RRD) in the myopic eye, by using multifocal electroretinography (mfERG). Both eyes from 12 patients were used to analyze the amplitude and latency of the first negative and positive mfERG first-order kernel components averaged over the entire stimulation area, by rings, quadrants of vision fields and in the areas of the adjacent and detached retina. The myopic eye in RRD even without macular involvement showed a selective reduction in R1 amplitude when central retinal rings 1 and 2 were stimulated, which suggests that the macular region is highly sensitive to the impaired anatomic integrity of the adjoining retinal zones.