Diagnostic characteristics of serological tests for the detection of SARS-CoV-2 cases.

To study the diagnostic characteristics of test systems for detecting antibodies to SARS-Cov-2. We studied the diagnostic characteristics of two test systems for detecting antibodies to SARS-Cov-2, registered in the Russian Federation. The first test system is a kit for detecting total antibodies to SARS-Cov-2 using immunochemiluminescence analysis on the «Cobas e 411» analyzer («Roche Diagnostics», Germany).

[Down's syndrome with congenital acute leukemia and congenital heart disease].

Objective: To report a rare case of Down's syndrome with congenital acute leukemia and congenital heart disease.

Material And Methods: We have retrospectively analyzed an electronic database of patients aged 0-17 years who underwent inpatient treatment of congenital heart disease at the Federal Center for Cardiovascular Surgery for the period from January 1, 2010 to December 31, 2018. Incidence of Down's syndrome in children with congenital heart defects was 5.

[Improving the quality of hematological studies using sigmametry.].

The purpose - evaluated the quality of the implementation of hematology studies using sigmametry. Studies were perfomed at the Federal state budgetary establishment "Federal center cardiovascular surgery". The data were collected in the period for 2017 y.

[The reference intervals of antithrombin III in population of the Astrakhanskaia oblast at application of automated coagulometers.].

The foreign and national professional societies of laboratory diagnostic recommend to every laboratory to develop own or substantiate available in literature reference intervals for every laboratory index. The reference interval of antithrombin III was established for adult population of the Astrakhanskaia oblast according available standards on automated coagulometers "ACL 9000" (Instrumentation Laboratory, USA) and "STA Compact" (Diagnostica Stago, France). The received data were compared with data present in instructions to reactive kits for detection of antithrombin III and reference literature.