Role of HLA genes in development of HLA-alloimmunization in blood recipients.

A genetically determined predisposition to the development of HLA-alloimmunization as a result of blood transfusions is associated with the presence of HLA-alleles DRB1*04, DQA1*03:01, DQA1*05:01 and HLA-haplotype DRB1*04-DQA1*03:01-DQB1*03:02 in the genotypes of recipients. The risk of antibody production is reduced in patients with HLA-alleles DRB1*16, DQA1*01:02, DQB1*05:02 and HLA-haplotype DRB1*16-DQA1*01:02-DQB1*05:02.

Continuous-Wave and Passively Mode-Locked Operation of a Cunyite (Cr(4+):Ca(2)GeO(4)) Laser.

Continuous-wave and mode-locked Cr(4+):Ca(2)GeO(4) lasers that use a fiber laser pump source were demonstrated. The continuous-wave Cr(4+):Ca(2)GeO(4) laser yielded a maximum output power of 415 mW at 1420 nm and a tuning range of 1335-1492 nm. With a saturable-absorber mirror, 60-ps pulses and 110-mW maximum output power were generated from a passively mode-locked Cr(4+):Ca(2)GeO(4) laser.

[The scientific justification of the new organizational forms and the normative base of medical care provision to the patients with pathology of the musculoskeletal system and connective tissue].

In the Russian Federation and all over the world as well the marked tendency of increasing of the diseases of musculoskeletal system and connective tissue, including vertebrogenic pathology is marked. The article presents the profound analysis of the vertebrogenic morbidity of pubescent population. In the experimental conditions, the scientific justification was given to the functional organizational model of day-stay hospital for the patients with vertebrogenic pathology.