Synthetic Thymidine Analog Labeling without Misconceptions.

Tagging proliferating cells with thymidine analogs is an indispensable research tool; however, the issue of the potential in vivo cytotoxicity of these compounds remains unresolved. Here, we address these concerns by examining the effects of BrdU and EdU on adult hippocampal neurogenesis and EdU on the perinatal somatic development of mice. We show that, in a wide range of doses, EdU and BrdU label similar numbers of cells in the dentate gyrus shortly after administration.

Influence of Modified Epoxy Dian Resin on Properties of Nitrile-Butadiene Rubber (NBR).

Due to the increasingly higher requirements for rubber vulcanizates, following the example of previous research on the effect of resin addition on mechanical properties and adhesion of rubbers, the following studies investigated the relationship between the addition of adipic acid-modified epoxy dian resin (ED-24 AK) to butadiene-acrylonitrile rubber (NBR). It can be seen that the addition of ED-24 AK, compared to the reference additive ED-20 (Epidian 5), additionally increase crosslinking density of the system, changes its mechanical and tribological properties, and exerts a positive effect on adhesion of the rubber vulcanizates to glass fiber. ED-20 and ED-24 AK resins do not enter the structure of the vulcanized rubber but act as the additives.

Microwave-Assisted Synthesis of Modified Glycidyl Methacrylate-Ethyl Methacrylate Oligomers, Their Physico-Chemical and Biological Characteristics.

In this study, well-known oligomers containing ethyl methacrylate (EMA) and glycidyl methacrylate (GMA) components for the synthesis of the oligomeric network [P(EMA)--(GMA)] were used. In order to change the hydrophobic character of the [P(EMA)--(GMA)] to a more hydrophilic one, the oligomeric chain was functionalized with ethanolamine, xylitol (Xyl), and L-ornithine. The oligomeric materials were characterized by nuclear magnetic resonance and Fourier transform infrared spectroscopy, scanning electron microscopy, and differential thermogravimetric analysis.

Influence of Modified Epoxy Resins on Peroxide Curing, Mechanical Properties and Adhesion of SBR, NBR and XNBR to Silver Wires. Part I: Application of Monoperoxy Derivative of Epoxy Resin (PO).

The research was aimed at checking the effect of monoperoxy derivative of epoxy resin (PO) on the possibility of rubber crosslinking and a subsequent adhesion of the modified rubber to silver wires. Three of the commonly industrially used rubbers were selected for the study: styrene-butadiene rubber (SBR), acrylonitrile-butadiene rubber (NBR) and carboxylated acrylonitrile-butadiene rubber (XNBR), together with the popular, commercially available Epidian 6 epoxy resin, subjected to the functionalization. An improvement in the adhesion of rubbers to silver wires was observed when using the modified resin.

Influence of Modified Epoxy Resins on Peroxide Curing, Mechanical Properties and Adhesion of SBR, NBR and XNBR to Silver Wires-Part II: Application of Carboxy-Containing Peroxy Oligomer (CPO).

This research was aimed at verifying the effect of carboxy-containing peroxy oligomer (CPO) addition on the possibility of rubber crosslinking and a subsequent adhesion of the modified rubber to silver wires. Three commonly industrially used rubbers were selected for the study: styrene-butadiene rubber (SBR), acrylonitrile-butadiene rubber (NBR) and carboxylated acrylonitrile-butadiene rubber (XNBR), together with carboxy-containing peroxy oligomer (CPO). An improvement in the adhesion of rubbers to silver wires was observed when applying the oligomeric peroxide with functional groups, with no deterioration of mechanical properties of the vulcanizates.