Wearable device for iontophoretic treatment and monitoring of pressure ulcers: Proof-of-concept.

This work demonstrates the feasibility of an all-in-one system for the detection, monitoring and treatment of pressure ulcers using two non-invasive methods, namely impedance spectroscopy and transdermal drug delivery by iontophoresis. The purpose of this device is to detect these chronic skin wounds at an early stage and treat them locally by delivering a vasodilator. The developed wearable flexible electrodes coupled to the compact electronic device used as a controlled current source show an increase in drug penetration by a factor of up to 8 for a current of 250 µA in comparison to passive diffusion.

Levels and distribution of organochlorine pesticides, polychlorinated biphenyls and polybrominated diphenyl ethers in sediments and biota from the Danube Delta, Romania.

Concentrations of polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) and organochlorine pesticides (OCPs), such as dichlorodiphenyltrichloroethane (DDT) and analogues, hexachlorocyclohexanes (HCHs) and hexachlorobenzene (HCB), were measured in sediments and biota (invertebrates, 11 fish species and cormorant tissues) collected in 2001 from the Danube Delta, the biggest European wetland. DDTs were the predominant pollutants in all samples. A high variability in the concentrations of pollutants within the same species was observed and this was related to sampling location, age, length and sex.