Publications by authors named "O Horn"
Article Synopsis
- A study surveyed 4,037 Canadian adults to estimate the prevalence of insomnia and the use of sleep aids, finding that 16.3% reported insomnia, with higher rates among women, Indigenous peoples, and those with poorer health.
- About 14.7% of respondents used prescribed sleep medications in the past year, while 28.7% used natural or over-the-counter options, 15.6% used cannabis products, and 9.7% used alcohol for sleep.
- The results emphasize the widespread issue of insomnia in Canada and the need for public health initiatives and effective treatments like cognitive behavioral therapy to improve sleep health.
Objective: The Memory Binding Test (MBT) shows promise in detecting early cognitive changes associated with Alzheimer's disease (AD). This study assesses the psychometric properties (i.e.
View Article and Find Full Text PDFA phase I trial of accelerated intermittent theta burst rTMS for amnestic MCI.
J Neurol Neurosurg Psychiatry
October 2024
Background: Emerging evidence suggests that repetitive transcranial magnetic stimulation (rTMS) enhances cognition in mild cognitive impairment (MCI). Accelerated intermittent theta burst stimulation (iTBS) rTMS protocols are promising as they substantially reduce burden by shortening the treatment course, but the safety, feasibility, and acceptability of iTBS have not been established in MCI.
Methods: 24 older adults with amnestic MCI (aMCI) due to possible Alzheimer's disease enrolled in a phase I trial of open-label accelerated iTBS to the left dorsolateral prefrontal cortex (8 stimulation sessions of 600 pulses of iTBS/day for 3 days).
Background: Neurodegeneration in Alzheimer's disease (AD) is typically assessed through brain MRI. Although proprietary software can provide normative estimates of regional atrophy, such tools can be cost-prohibitive for research settings. Free software for generating normative estimates has recently been released but has yet to be validated in the context of amnestic mild cognitive impairment (aMCI).
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