INFLUENCE OF THE ACTING SUBSTANCE SODIUM DICLOFENAC ON BONE MARROW CELLS.

In humans and mammals, the homeostasis system is supported by many organs and systems, but hematopoietic remains one of the most important. A negative effect on the hematopoietic system is rejected by many factors, but the first place remains for drugs, which one in three are non-steroidal anti-inflammatory drugs (NSAIDs). The most popular among them remains the active substance "Diclofenac Sodium", which is part of many drugs.

The dynamics of changes in biochemical markers of the state of tissue in intercostal muscles during the early postmortem period.

Aim: The aim of study was to evaluate structural and biochemical changes in the tissue of intercostal muscles during the early postmortem period (PMP) - 3-13 hours.

Materials And Methods: Absolute and relative values of the concentration of glycogen, acid phosphatase, lactate, lactate degydrogenase, lipofuscin and cholinesterase during the early PMP were determined on 30 human corpses by results of study of the tissue of intercostal muscles.

Results: It was proved that the early PMP was characterized by proper biochemical and biophysical changes of the muscular tissue, the most demonstrative of them were as follows: a reduction in the concentration of glycogen and dynamic increases in the concentrations of lactate dehydrogenase and lipofuscin.

Study of structural and biochemical changes in the muscular tissue of the oesophagus for solving the problem of diagnosing the prescription of death coming.

Unlabelled: The modern practice and tactics of forensic medical diagnosis require scientific substantiation of informative diagnostic criteria for assessing the prescription of death coming (PDC), first of all during the early postmortem period (PMP).

Aim: The aim of the study was an evaluation of the concentration changes of biochemical markers (BCM) in muscular tissue (MT) of the oesophagus during the early postmortem period.

Materials And Methods: MT of the oesophagus within the period of 3-13 hours after the coming of death was studied on 30 human corpses.