Publications by authors named "O H Ng"
High Dyspnea Score, a Trigger for Specialist Palliative Care Utilization-Results from a Cohort Study on the Predictors of High Opioid and Benzodiazepine Use in COVID-19 Patients.
Lionel Kee Yon See Mahrley Tanagon Provido Sheryl Ng Fionna Chunru Yow Xin Lun Ho Oon Tek Ng Wen Yang Goh
J Palliat Med
November 2024
Article Synopsis
- - Patients with severe COVID-19 often experience rapid worsening of symptoms, particularly dyspnea, necessitating early involvement of specialist palliative care (SPC) for effective symptom management and end-of-life care.
- - A study at the National Centre for Infectious Diseases in Singapore analyzed nonventilated COVID-19 patients between January 2021 and July 2022 to identify risk factors for high use of opioids and benzodiazepines in managing dyspnea.
- - Findings revealed that patients with higher dyspnea scores and lower ISARIC-4C mortality scores were more likely to be high users of these medications, indicating they have increased oxygen needs and higher mortality rates, thus highlighting the need for timely
Article Synopsis
- * This study highlights a case of a 16-year-old boy with gastric signet ring cells and a germline CDH1 pathogenic variant, along with a known family history of early gastric cancer.
- * Managing the cancer risk for him and his 9-year-old sister also carrying the CDH1 variant posed significant challenges for both medical professionals and their family, illustrating the complexity of early-onset hereditary cancer risks.
Article Synopsis
- - The study examines how cephalosporin-resistant E. coli spreads in tropical waters of Singapore by analyzing samples from various sources between 2016 and 2020.
- - Researchers found strong genetic similarities between E. coli from the environment and hospitals, particularly the concerning pandemic strain ST131, indicating high resistance due to mutations and mobile genetic elements.
- - Pathogenic strains linked to public health threats were discovered in community sewage and aquaculture areas, highlighting the important connection between human activities and environmental health issues related to antibiotic resistance.