Publications by authors named "O Gurbuz"
Background: To our knowledge, a possible predictive relationship of the multi-inflammatory index (MII) with new-onset atrial fibrillation (AF) after off-pump coronary artery bypass grafting (CABG) has not yet been studied in the literature.
Aims: We aimed to investigate whether the MII is a novel group of hematological markers for predicting postoperative new-onset AF in patients undergoing off-pump CABG.
Methods: A total of 427 patients undergoing isolated off-pump CABG between October 2021 and December 2023 were enrolled in this retrospective observational cohort study and allocated to two groups: the AF group (n = 108) and the non-AF group (n = 319).
More than a year after COVID-19 was declared a pandemic by the World Health Organization, the U.S.A.
View Article and Find Full Text PDFThe COVID-19 pandemic catalyzed the swift development and distribution of mRNA vaccines, including BNT162b2, to address the disease. Concerns have arisen about the potential neurodevelopmental implications of these vaccines, especially in susceptible groups such as pregnant women and their offspring. This study aimed to investigate the gene expression of WNT, brain-derived neurotrophic factor (BDNF) levels, specific cytokines, m-TOR expression, neuropathology, and autism-related neurobehavioral outcomes in a rat model.
View Article and Find Full Text PDFPrognostic value of CHADS-VASc score for the long-term cardiovascular events after coronary artery bypass grafting.
Turk Gogus Kalp Damar Cerrahisi Derg
October 2023
Background: This study aims to investigate the value of the CHA2DS2-VASc score in predicting long-term major cardiovascular events following coronary artery bypass grafting.
Methods: Between January 2008 and January 2010, a total of 559 patients (445 males, 114 females; mean age: 62.7±9.
Article Synopsis
- Retinoblastoma is a rare eye cancer in children caused by the inactivation of the RB1 gene, linked to genetic and epigenetic factors, specifically the methylation of the RB1 gene promoter.
- A study screened 50 familial retinoblastoma patients for RB1 promoter methylation compared to 52 healthy controls matched by age, sex, and ethnicity, using real-time PCR.
- The results showed no significant difference in methylation levels between the retinoblastoma patients (36.1%) and controls (33.9%), suggesting that RB1 promoter methylation does not affect the hereditary nature of the disease.