Practical implementation of automated insulin delivery systems in 2025: A French position statement update.

The advent of automated insulin delivery (AID) systems in 2020 marked a disruptive event in managing type 1 diabetes, benefiting children and adults alike. By 2024, advances in real-world data and research motivated an update to the French consensus on AID systems to expand accessibility, refine guidelines, and optimize patient follow-up. AID systems have consistently improved glycemic control by reducing HbA1c, increasing time-in-range (TIR), and minimizing hypoglycemia, with significant benefits even for specific populations such as individuals with poor glycemic control, brittle diabetes, children, very young children, pregnant women, those with insulin resistance or gastroparesis, or after bariatric surgery.

A first-principles study of interfacial vacancies in the β-CsPbI/1T-MoS heterostructure towards photocatalytic applications.

Halide perovskite (HP) composites with transition metal dichalcogenides (TMDs) have attracted attention as promising photocatalysts for hydrogen production through solar-driven water splitting but their working mechanism is yet unclear. Here, we propose novel heterostructures composed of all-inorganic HP β-CsPbI and metallic TMD 1T-MoS and investigate the influence of interfacial vacancies on their interfacial properties using first-principles calculations. Using CsPbI(001)/MoS(001) interface slab models with a minimal lattice mismatch, we calculate the interface formation and interlayer binding energies, finding that the PbI-terminated interfaces have better stability and stronger binding strength than the CsI-terminated ones and iodine vacancy enhances the binding properties.

Development and Validation of the Patient-Level Chinese Diabetes Outcome Model on Long-term Complications in Type 2 Diabetes: An Application of the Hong Kong Diabetes Register.

Objective: Patient-level simulation models, mainly developed in Western populations, capture complex interactions between risk factors and complications to predict the long-term effectiveness and cost-effectiveness of novel treatments and identify high-risk subgroups for personalized care. However, incidence of outcomes varies significantly by ethnicity and region. We used high-quality, patient-level register data to develop the Chinese Diabetes Outcomes Model (CDOM) for predicting incident and recurrent events in type 2 diabetes (T2D).

Concomitant ATTR and AL Cardiac Amyloidosis With Matching 99mTc-DPD Scintigraphy and 18F-Flutemetamol PET/CT.

Two distinct types of systemic amyloidosis-transthyretin (ATTR) and light chain (AL)-account for the majority of cardiac amyloidosis (CA), which have been considered mutually exclusive. Diagnostic confusion can arise when both proteins are identified from an amyloid deposit. We present a rare occurrence of histopathologically confirmed concomitant ATTR and AL CA captured on 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and 18F-flutemetamol (FMM) PET/CT.

MacaqueNet: Advancing comparative behavioural research through large-scale collaboration.

There is a vast and ever-accumulating amount of behavioural data on individually recognised animals, an incredible resource to shed light on the ecological and evolutionary drivers of variation in animal behaviour. Yet, the full potential of such data lies in comparative research across taxa with distinct life histories and ecologies. Substantial challenges impede systematic comparisons, one of which is the lack of persistent, accessible and standardised databases.