Publications by authors named "O Grip"
Article Synopsis
- The study aimed to find protein signatures in blood that could help identify individuals at high risk for inflammatory bowel disease (IBD), specifically Crohn's disease (CD) and ulcerative colitis.
- Researchers analyzed blood samples from a large population, utilizing machine-learning methods to identify and validate these protein signatures across multiple cohorts.
- A specific combination of 29 proteins was effective in differentiating preclinical CD cases from controls, achieving a high accuracy, while the prediction for ulcerative colitis was less robust but still significant.
The care of IBD patients aims to achieve the best possible health. The treatment goals in IBD should therefore, in addition to stable control of intestinal inflammation, also consider health-related quality of life (HRQL) and extraintestinal complications. Fatigue is an underrecognized array of symptoms that need more attention and, if possible, treatment.
View Article and Find Full Text PDFBackground: Nutri-score is now widely available in food packages in Europe.
Aim: To study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort METHODS: We collected dietary data at baseline from validated food frequency questionnaires. We used a dietary index based on the UK Food Standards Agency modified nutrient profiling system (FSAm-NPS-DI) underlying the Nutri-Score label, to measure the nutritional quality of the diet.
Article Synopsis
- The study assessed long-term outcomes of vedolizumab (VDZ) over three years for patients with inflammatory bowel disease (IBD), specifically Crohn's disease (CD) and ulcerative colitis (UC).
- High continuation rates of VDZ treatment were observed, with 88% of CD patients and 87% of UC patients still on the medication after 104 weeks.
- Significant improvements were reported in clinical remission rates and health-related quality of life, with decreases in inflammatory markers, indicating VDZ is an effective long-term treatment for IBD.
Background & Aims: Industrial foods have been associated with increased risks of several chronic conditions. We investigated the relationship between the degree of food processing and risks of Crohn's disease (CD) and ulcerative colitis (UC) in the European Prospective Investigation into Cancer and Nutrition cohort.
Methods: Analyses included 413,590 participants (68.