Publications by authors named "O Gaillot"
Article Synopsis
- - The study investigates how intestinal colonization with multidrug-resistant Enterobacterales (MDRE-IC) affects the risk of bloodstream infections (nE-BSI) in hospitalized patients, finding that MDRE-IC significantly increases this risk.
- - Conducted at a large hospital in 2019, the research involved over 7000 patients, with 11.9% found to have MDRE-IC; those colonized had a higher incidence of nE-BSI compared to non-colonized patients.
- - The results highlight the importance of improving infection control and antibiotic use strategies in hospitals to reduce the risk of bloodstream infections related to MDRE colonization.
Background: Intestinal clearance of carbapenemase-producing Enterobacterales (CPE-IC) is a cornerstone to discontinue isolation precautions for CPE patients in hospitals. This study aimed to evaluate the time to spontaneous CPE-IC and identify its potential associated risk factors.
Methods: This retrospective cohort study was carried out between January 2018 and September 2020 on all patients in a 3200-bed teaching referral hospital with confirmed CPE intestinal carriage.
Recent reports have indicated a rise of invasive disease caused by serotype a (Hia) in North America and some European countries. The whole-genome sequences for a total of 410 invasive Hia isolates were obtained from 12 countries spanning the years of 1998 to 2019 and underwent phylogenetic and comparative genomic analysis in order to characterize the major strains causing disease and the genetic variation present among factors contributing to virulence and antimicrobial resistance. Among 410 isolate sequences received, 408 passed our quality control and underwent genomic analysis.
View Article and Find Full Text PDFBackground: The carriage of carbapenemase-producing Enterobacteriaceae (CPE) might lengthen the time to functional recovery (TTFR) for inpatients in post-acute care (PAC) units.
Objective: We aimed to assess the impact of CPE carriage on TTFR in a PAC facility.
Methods: This 2-year retrospective cohort study included 20 CPE-positive patients and 54 CPE-negative patients admitted to 3 PAC units (general, orthopaedic and neurological rehabilitation units) in a teaching hospital from January 2017 to December 2019.