[The role of bone marrow macrophages in regulating erythropoiesis in different states of the erythron].

Stimulation and inhibition of erythropoiesis were modelled in rats to study the functional condition of central macrophages of the erythroblastic islets (EI) in the bone marrow by determining the total content of lysosomes, pH of lysosomes, activity of acid phosphatase, and 3H-thymidine inclusion in DNA. The properties of the surface charges of the EI cells were judged according to the electrophoretic mobility, the number of acid glycoproteins--according to the staining of the preparations with alcian blue. It is shown that the intensity of erythropoiesis in the EI determines the studied values.

[The mechanisms of cellular complementarity in the erythroblast islands of the bone marrow].

Phenylhydrazine was shown to reduce the content of erythroblast islands (EI) within 24 hrs in the rat bone marrow, the effect depending on the dose. Simultaneous strengthening of phagocytic activity, acidifying of lysosomes central macrophages EI and lowering of electrophoretic mobility, were observed. The proteinase inhibitor contrycal (50 and 500 i.