[Focus on the Odon Device™: Technical improvements, mechanical principles and progress of the clinical research program].

The Odon Device™ has been described in the literature since 2013 and the World Health Organization supports its development through the Human Reproduction Program. This innovative device could be easier to use than usual instruments and could be an alternative to caesarean section during the second stage of labor, especially in countries where access to obstetric care is limited. The aim of the Odon Device™ is to position an air cuff over the fetal head, past its widest point (around the level of the fetal mouth anteriorly and the nape of the fetal neck posteriorly).

Extremely premature infants: How does death in the delivery room influence mortality rates in two level 3 centers in France?

Objectives: Mortality rates of very preterm infants may vary considerably between healthcare facilities depending on the neonates' place of inclusion in the cohort study. The objective of this study was to compare the mortality rates of live-born extremely preterm neonates observed in two French tertiary referral hospitals, taking into account the occurrence of neonatal death both in the delivery room and in the neonatal intensive care unit (NICU).

Methods: Retrospective observational study including all pregnancy terminations, stillbirths and live-born infants within a 22- to 26-week gestational age range was registered by two French level 3 university centers between 2009 and 2013.

Identification of new Corynebacterium pseudotuberculosis antigens by immunoscreening of gene expression library.

Background: Caseous lymphadenitis (CLA) is a disease that affects sheep, goats and occasionally humans. The etiologic agent is the Corynebacterium pseudotuberculosis bacillus. The objective of this study was to build a gene expression library from C.

Reactome pathway analysis: a high-performance in-memory approach.

Background: Reactome aims to provide bioinformatics tools for visualisation, interpretation and analysis of pathway knowledge to support basic research, genome analysis, modelling, systems biology and education. Pathway analysis methods have a broad range of applications in physiological and biomedical research; one of the main problems, from the analysis methods performance point of view, is the constantly increasing size of the data samples.

Results: Here, we present a new high-performance in-memory implementation of the well-established over-representation analysis method.