Background: Breslow density (BD) is an estimation of melanoma volume, which has emerged as a novel histopathological prognostic biomarker.
Objectives: To evaluate the role of BD as a predictor of patients' survival and assess its prognostic value in relation to overall survival (OS), disease-free survival (DFS), melanoma-specific survival (MSS) and metastasis-free survival (MFS).
Methods: A retrospective observational study in a cohort of 107 patients with invasive melanoma was conducted.
Background: Current staging systems have limitations in stratifying high-risk cutaneous squamous cell carcinoma (cSCC). Tumour budding (TB) has emerged as a potential prognostic factor in various cancers.
Objectives: To evaluate the prognostic significance of TB in predicting lymph node metastases (NM) in cSCC.
Australas J Dermatol
November 2023
Reconstruction of surgical defects after wide local excision of acral melanoma on the sole should allow patients to walk and bear weight. Moreover, certain options such as local transposition flaps can compromise follow-up. We present a case series of surgical defects on weight-bearing areas of the sole reconstructed using a synthetic dermal matrix and a split-thickness skin graft.
View Article and Find Full Text PDFBackground: The COVID-19 lockdown possibly meant a delay in the diagnosis and treatment of melanoma and therefore, worsening its prognosis. This unique situation of diagnosis deferral is an exceptional opportunity to investigate melanoma biology.
Objectives: To evaluate the immediate and mid-term impact of diagnosis delay on melanoma.