Publications by authors named "O Fichaux"
Article Synopsis
- Despite advancements in stent technology, there's still a notable risk of in-stent restenosis (ISR) after procedures like PCI, and comprehensive data on this issue is limited.
- A study analyzed data from the France-PCI registry between 2014 and 2018, focusing on patients with ISR lesions, finding that 7.3% of the patients treated had ISR PCI, mostly involving older individuals with comorbidities like diabetes.
- The results revealed that those undergoing ISR PCI had higher rates of complications after one year compared to non-ISR patients, indicating a need for further research and improved techniques in managing ISR.
Objectives: We sought to compare, in a national French registry (FrancePCI), the clinical impact of fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) compared with angio-guided PCI at 1 year.
Background: FFR has become the invasive gold standard to quantify myocardial ischemia generated by a coronary stenosis in patients with chronic coronary syndrome, but in clinical practice it is still underutilised to guide PCI compared to angiography (angio).
Methods: We extracted from the FrancePCI database all chronic coronary syndrome patients treated with PCI for coronary stenosis <90% between 2014 and 2019.
Growing use of fractional flow reserve (FFR) and intracoronary imaging techniques by optical coherence tomography or intravascular ultrasound has raised concerns about additional exposure during coronary angiography and percutaneous coronary interventions (PCIs). Using data from the prospective CRAC-France PCI Prospective Multicentre registry, we sought to evaluate the effect of these new techniques on the radiation dose to patients undergoing coronary procedures. Data on Kerma Area Product (PKA), total air kerma (KAr) and fluoroscopy time from 42 182 coronary procedures were retrospectively compared, using multivariable linear regression, according to whether they included FFR and intracoronary imaging.
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- STEMI patients with multivessel disease (MVD) generally have a worse prognosis, but recent studies suggest this gap might have narrowed with improved treatment.
- The study analyzed 1,886 STEMI patients who received timely primary PCI to compare outcomes based on the number of diseased vessels (one-, two-, and three-vessel disease).
- Results indicated that at one year, the rates of major adverse cardiovascular events (MACE) were similar across different vessel disease groups, suggesting that the prognosis for MVD patients may not be as poor as previously thought in modern medical settings.
Incidence, delays, and outcomes of STEMI during COVID-19 outbreak: Analysis from the France PCI registry.
J Am Coll Emerg Physicians Open
December 2020
Article Synopsis
- The study examined how COVID-19 affected the incidence, delays, and outcomes for STEMI patients receiving primary PCI in France.
- A total of 2064 patients were analyzed, revealing a 12% drop in monthly STEMI cases during lockdown, along with increased delays in getting medical help.
- Although in-hospital major adverse cardiac events and mortality rates were higher during lockdown, the increases were not statistically significant.