[The intravesical administration of BCG vaccine in treating recurrent superficial bladder cancer].

The authors consider general immunological effects of intravesical BCG vaccine as an independent method of immunotherapy of superficial cancer of the bladder (CB). 27 patients (15 males and 12 females, mean age 57 years) with a recurrence of superficial CB (T1-2N0M0) were treated. The patients had undergone transurethral or transvesical bladder resection and combined therapy.

[The immunomodulating action of bestatin in the combined therapy of bladder cancer patients].

A beneficial effect of bestatin used as adjuvant in the course of chemo- and radiotherapy of local cancer of the bladder manifested itself as a reduction of postradiation immunosuppression: increased count of T mu-helper/inductors and T gamma-suppressors/killers, enhancement of neutrophil phagocytic activity. Bestatin recovers radiation-impaired immune system by inhibition of T gamma-suppressor killers and their precursors generation, of endogenic regulators suppressive activity, normalization of T-lymphocyte and natural killer activity, stimulation of B-lymphocyte recovery.

[Osteogenic sarcoma in children: clinico-immunological correlations].

Initial immunologic status in children suffering osteogenic sarcoma was retrospectively evaluated versus such parameters as site and extent of tumor, and clinical course. A complex of disorders in the immunologic system was established in osteogenic sarcoma patients. Such characteristics as levels of active, theophylline--sensitive and levamisole--reactivated T-cells were found clinically valuable and prognostically significant.