[Some conceptual aspects in studies of the autonomic nervous system].

As a result of intensive research performed in different laboratories recent years in the field of autonomic nervous system physiology, considerable experimental material was collected and some new and interesting hypotheses were proposed. This review is a short sketch about the progress in the study of autonomic transmission mechanisms. Since the sixties of the last century non-adrenergic non-cholinergic nerves were opened, and it was the later recognition of a multiplicity of neurotransmitter substances in autonomic nerves.

[Synaptic responses and intraganglionic connections of rat superior cervical ganglia neurons].

The rat superior cervical ganglion (SCG) neurones demonstrate responses on the threshold stimulation of the cervical sympathetic nerve, extrinsic (ECN) and intrinsic (ICN) carotid nerves. Both antidromic and synaptic responses were evoked by antidromic stimulation of ECN and ICN. The synaptic responses of each neuron differ by great variability amplitudes of the excitatory postsynaptic potentials and the currents, the rise time and the time constant decay of the postsynaptic current.

[The pharmacological blockade of the cardiac and gastric enteric ganglia by a new parasympatholytic].

The blocking effects of a newly synthetized compound N-decyltropine bromide (IEM-1556), on pentagastrin-, carbachol- and histamine-induced gastric secretion in chronic dogs, on stress-induced changes in gastric mucosa in rats, on vagus-induced effect in heart and on arterial blood pressure in rats were studied. The effects were compared with those produced by hexamethonium, a conventional ganglionic blocking agent. IEM-1556 inhibited gastric secretion and acid output for a much longer time than hexamethonium did.