[Effect of induction of the synthesis of serotonin antibodies on lipid peroxidation in experimental alcoholism].

The effect of antibodies to serotonin on lipid peroxidation (LPO) in acute alcoholic intoxication was studied in rabbit experiments. Acute alcoholization causes marked LPO disorders which are manifested by a sharp increase of the content of intermediate products and reduction of the concentration of end products. Active immunization of the animals with a conjugated serotonin antigen, bovine serum albumin, reduces the LPO disorders induced by alcoholization.