Occurrence of emerging and persistent organic pollutants in the rivers Cam, Ouse and Thames, UK.

The widespread occurrence of new and emerging and persistent organic pollutants (NEPs and POPs) in surface water poses a risk to drinking water supply and consequently human health. The aim of this work was to investigate the occurrence and potential transport of 42 target NEPs and POPs (including per-and polyfluoroalkyl substances (PFAS), pharmaceuticals, pesticides and bisphenols) along the rural and urban environments of three rivers in England. The type and concentrations of pollutants varied between the sampling days and points.

Unveiling the nexus: The tumor microenvironment as a strategic frontier in viral cancers.

Viral infections are a significant factor in the etiology of various cancers, with the tumor microenvironment (TME) playing a crucial role in disease progression. This review delves into the complex interactions between viruses and the TME, highlighting how these interactions shape the course of viral cancers. We explore the distinct roles of immune cells, including T-cells, B-cells, macrophages, and dendritic cells, within the TME and their influence on cancer progression.

Effect of short-term sample storage and preparatory conditions on losses of 18 per- and polyfluoroalkyl substances (PFAS) to container materials.

There is a lack of agreement on a suitable container material for per- and polyfluoroalkyl substances (PFAS) analysis, particularly at trace levels. In this study, the losses of 18 short- and long-chain (C4-C10) PFAS to commonly used labware materials (high-density polyethylene (HDPE), polypropylene (PP), polystyrene (PS), polypropylene co-polymer (PPCO), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and glass were investigated. The influence of sample storage and preparation conditions, i.

A case report of tracheal tenting to the skin: An option to tracheostomy for post-thyroidectomy tracheomalacia.

Operating on a huge and long-standing goiter is challenging to the surgeon and anesthetist because of the possibility of tracheomalacia and collapse of the tracheal rings after extubation. We report our innovation of tenting the trachea to the skin using sutures (passed through the strap and sternocleidomastoid muscles) to prevent post-thyroidectomy tracheomalacia.

A new on-line SPE LC-HRMS method for simultaneous analysis of selected emerging contaminants in surface waters.

In recent years emerging contaminants (ECs) have received significant attention due to their widespread detection in surface waters and concerns that these compounds can cause adverse ecological and/or human health effects. Therefore, accurate methods for determining and quantifying ECs in surface water are essential for estimating their environmental impact. This work describes the development, validation and application of a sensitive multiclass method for simultaneous determination of 22 per and polyfluorinated alkyl substances (PFASs), 3 pharmaceuticals, 15 pesticides, and 2 bisphenols in surface water using on-line solid phase extraction (SPE) coupled with ultra-performance liquid chromatography-high-resolution mass spectrometry (UPLC-HRMS).