Publications by authors named "O Dilek"
Background/objectives: The aim was to investigate the association between variations in the dorsal pancreatic artery (DPA) and intrapancreatic arcade anatomy with Whipple procedure outcomes and postoperative complications.
Methods: This retrospective study was conducted with 362 patients who underwent a Whipple procedure at the Department of Gastroenterological Surgery of Adana City Training and Research Hospital between January 2018 and April 2024. All data collected from medical records were compared and statistically analyzed according to the patients' survival status and arcade subtypes.
Large-scale defects of body in the reconstructive surgical practice, and the helplessness of their repair with autologous tissues, have been an important factor in the development of artificial biological products for the temporary, definitive, or staged repair of these defects. A major advance in the field of plastic and other reconstructive surgery in this regard has been the introduction and successful use of acellular dermal matrices (ADMs). In recent years, not only the type of tissue from which ADMs are produced, product range, diversity and areas of use have increased, but their use in reconstructive fields, especially in post oncologic breast surgery, has become highly regarded and this has favored ADMs to be a potential cornerstone in specific and well-defined surgical fields in future.
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- - Protein carbonylation is a key irreversible modification that indicates oxidative stress but lacks distinct spectroscopic properties, making it challenging to detect without specific chemical probes.
- - The protocol details the synthesis of a new fluorescent probe, 2Hzin5NP, which reacts rapidly with carbonyls to create a detectable product, and outlines the methods to evaluate its effects on cell health and carbonylation.
- - The probe can differentiate carbonylation profiles in response to oxidative stress in healthy and cancerous cells, providing insight into varying oxidative stress levels between these conditions.
Article Synopsis
- The study assessed how well three radiologists agreed on MRI evaluations for staging and restaging rectal cancer in 239 patients, particularly after neoadjuvant therapy.
- The findings showed moderate to high interobserver agreement on various MRI parameters, with specific focus on tumor distance from the mesorectal fascia and lymph node involvement being significant predictors of locoregional recurrence.
- Ultimately, the analysis highlighted the importance of lymph node restaging and its correlation with locoregional recurrence rates, indicating that changes in lymph node status can influence patient outcomes.