Publications by authors named "O De Lucia"
Aims: Electromagnetic induction heating has demonstrated in vitro antibacterial efficacy over biofilms on metallic biomaterials, although no in vivo studies have been published. Assessment of side effects, including thermal necrosis of adjacent tissue, would determine transferability into clinical practice. Our goal was to assess bone necrosis and antibacterial efficacy of induction heating on biofilm-infected implants in an in vivo setting.
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- The study aimed to explore the frequency and characteristics of tenosynovitis in young patients with new-onset juvenile idiopathic arthritis (JIA) who have active ankle disease and whether its detection impacts the likelihood of achieving inactive disease status.
- It involved 45 children, showing that 62.2% had tenosynovitis detected via ultrasound (US), while 37.8% had isolated arthritis, with no significant differences in achieving inactive disease between those with and without tenosynovitis.
- The findings suggest that even though tenosynovitis is common at the onset of JIA, it does not negatively affect the chances of reaching clinically inactive disease early in the treatment process.
Background: Periprosthetic joint infection is a serious complication following joint replacement. The development of bacterial biofilms bestows antibiotic resistance and restricts treatment via implant retention surgery. Electromagnetic induction heating is a novel technique for antibacterial treatment of metallic surfaces that has demonstrated in-vitro efficacy.
View Article and Find Full Text PDFTumor location on electroporation therapies by means of multi-electrode structures and machine learning.
Bioelectrochemistry
December 2023
Electroporation is a phenomenon produced in the cell membrane when it is exposed to high pulsed electric fields that increases its permeability. Among other application fields, this phenomenon can be exploited in a clinical environment for tumor ablation therapies. In this context to achieve optimum results, it is convenient to focus the treatment on the tumor tissue to minimize side effects.
View Article and Find Full Text PDFObjective: Synovitis and tenosynovitis are present in juvenile idiopathic arthritis (JIA), both as joint pain and/or inflammation, making them difficult to detect on physical examination. Although ultrasonography (US) allows for discrimination of the 2 entities, only definitions and scoring of synovitis in children have been established. This study was undertaken to produce consensus-based US definitions of tenosynovitis in JIA.
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