Publications by authors named "O Daly"
Seamless EMR data access: Integrated governance, digital health and the OMOP-CDM.
BMJ Health Care Inform
February 2024
Article Synopsis
- The Observational Medical Outcomes Partnership Common Data Model (OMOP-CDM) standardizes electronic medical record (EMR) data, making it easier for health service providers and researchers to access and analyze the data securely.
- It uses techniques like pseudonymisation and common data quality assessments to protect patient privacy while allowing for the efficient sharing of de-identified, aggregated data for research.
- By simplifying governance and promoting interoperability, the OMOP-CDM supports various clinical and epidemiological research initiatives, enabling faster and more accurate analysis across different healthcare systems without direct data exchange.
Argininosuccinic aciduria (ASA) is a metabolic disorder caused by a deficiency in argininosuccinate lyase (ASL), which cleaves argininosuccinic acid to arginine and fumarate in the urea cycle. ASL deficiency (ASLD) leads to hepatocyte dysfunction, hyperammonemia, encephalopathy, and respiratory alkalosis. Here we describe a novel therapeutic approach for treating ASA, based on nucleoside-modified messenger RNA (modRNA) formulated in lipid nanoparticles (LNP).
View Article and Find Full Text PDFBackground: The Australasian Pelvic Floor Procedure Registry (APFPR) captures clinical and surgical data in women undergoing pelvic floor procedures. The inclusion of patient reported outcome measures (PROMs) in the APFPR is a critical activity providing the additional patient perspective of their condition prior to surgery as well as monitoring beyond the usual post-surgical follow-up time. This study aimed to evaluate the acceptability of seven PROMs for women with pelvic organ prolapse (POP) and to determine the most suitable instrument for the APFPR.
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