Simultaneous Luminal and Hemodynamic Evaluation of the Cervical Arteries Using Nonenhanced 3D Quantitative Quiescent-Interval Slice-Selective Magnetic Resonance Angiography.

Background: Luminal and hemodynamic evaluations of the cervical arteries inform the diagnosis and management of patients with cervical arterial disease.

Purpose: To demonstrate a 3D nonenhanced quantitative quiescent interval slice-selective (qQISS) magnetic resonance angiographic (MRA) strategy that provides simultaneous hemodynamic and luminal evaluation of the cervical arteries.

Study Type: Prospective.

Effects of Vibration Therapy on Muscle Strength, Shoulder Range of Motion, and Muscle Biomechanical Properties in Patients with Breast Cancer Undergoing Radiotherapy: A Randomized Controlled Trial.

Objective: To investigate the effects of vibration therapy to home-based exercises on shoulder muscle strength, range of motion (ROM), pain-related disability, and muscles viscoelastic properties of shoulder and neck in patients with breast cancer undergoing radiotherapy.

Design: In this randomized controlled superiority trial was conducted with 38 participants who underwent breast cancer surgery. All patients were randomized into two groups: control group (CG) and vibration group (VG).

Quantifying thenar muscle biomechanical properties: Sex-based variations and implications for grip strength.

Background: Quantifying the biomechanical properties of the thenar muscle can provide valuable insight into hand assessment methods.

Purpose: This study aimed to examine the reliability of myotonometer measurements in determining the biomechanical properties (tone, stiffness and elasticity) of thenar muscles in healthy individuals and explore sex-based variations. Additionally, it assessed the relationship between pinch strength and these properties.

Quinazoline derivatives as novel bacterial sphingomyelinase enzyme inhibitors.

Bacillus cereus sphingomyelinase C (B. cereus SMase), which plays a crucial role in bacterial virulence, has emerged as a new therapeutic target for treating opportunistic infections caused by this pathogen. It also shares catalytic domain similarity with human neutral sphingomyelinase 2 (nSMase2), which is implicated in Alzheimer's disease.