Publications by authors named "O Coza"
Background: Clinical audits are an important tool to objectively assess clinical protocols, procedures, and processes and to detect deviations from good clinical practice. The main aim of this project is to determine adherence to a core set of consensus- based quality indicators and then to compare the institutions in order to identify best practices.
Materials And Methods: We conduct a multicentre, international clinical audit of six comprehensive cancer centres in Poland, Spain, Italy, Portugal, France, and Romania as a part of the project, known as IROCATES (Improving Quality in Radiation Oncology through Clinical Audits - Training and Education for Standardization).
Article Synopsis
- Precision medicine in lung cancer research has led to improved patient survival and quality of life, especially through targeted therapies for non-small cell lung cancer (NSCLC) with ALK gene rearrangement.* -
- This review highlights ALK tyrosine kinase inhibitors (TKIs), their mechanisms of action and resistance, various gene detection methods, and future research aimed at overcoming resistance.* -
- Crizotinib was the first approved TKI and while newer drugs like alectinib and brigatinib have been developed, resistance remains a significant challenge with half of the resistance mechanisms still unidentified.*
Ovarian cancer is one of the most common cancers worldwide, and is associated with a prior diagnosis of endometriosis in several cases. Our aim was to correlate genetic and methylation profile of ovarian endometrioid ovarian cancer and endometriosis patients. We evaluated the genetic profile of 50 ovarian endometriosis and 20 ovarian endometrioid carcinoma samples using next generation sequencing technology.
View Article and Find Full Text PDFColorectal cancer remains one of the most frequent malignancies (third place at both genders) worldwide in the last decade, owing to significant changes in modern dietary habits. Approximately half of the patients develop metastases during the course of their disease. The available therapeutic armamentarium is constantly evolving, raising questions regarding the best approach for improving survival.
View Article and Find Full Text PDFColorectal cancer (CRC) is the third most common cancer in Europe, with an annual increase in incidence ranging between 0.4 and 3.6% in various countries.
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