Publications by authors named "O Costa"

Article Synopsis
  • Cardiomyopathies in children and teenagers can lead to serious complications like heart failure, arrhythmias, and even sudden death, making early diagnosis crucial but challenging due to various symptoms and causes.
  • * Advances in precision medicine now allow for better molecular diagnosis, enabling tailored treatment plans and identifying family members at risk.
  • * This review outlines the unique aspects of pediatric cardiomyopathies and introduces a five-stage protocol for diagnosis and individualized therapy to improve patient outcomes.
View Article and Find Full Text PDF

Background: We have retrospectively reviewed our series of brain tumor patients operated on using 3D IntraOperative UltraSound (IOUS) to report technical advantages and areas of improvement.

Methods: Clinical and radiological data of patients with a diagnosis of high-grade glioma IV operated with and without IOUS were retrieved and analyzed.

Results: We have found 391 patients operated using IOUS coupled with neuronavigation and 257 using neuronavigation standalone.

View Article and Find Full Text PDF

Importance: Microplastic (MP) pollution is an emerging environmental and health concern. While MPs have been detected in various human tissues, their presence in the human brain has not been documented, raising important questions about potential neurotoxic effects and the mechanisms by which MPs might reach brain tissues.

Objective: To determine the presence of MPs in the human olfactory bulb and to analyze their characteristics such as size, morphology, color, and polymeric composition.

View Article and Find Full Text PDF

We address the hypothesis that at early and late lactation milk presents low ethanol stability due to high acidity and ionic calcium values. Our aim was to evaluate the functional traits of milk (milk ethanol stability: MES, acidity and ionic calcium: iCa) according to lactation stage in different genetic groups. Raw milk samples were collected from Jersey ( = 271), Holstein ( = 248) and Jersey × Holstein crossbred cows ( = 82), raised on five commercial farms located in the state of Paraná, Brazil.

View Article and Find Full Text PDF

Soybean cultivation in tropical regions relies on symbioses with nitrogen-fixing Bradyrhizobium and plant growth-promoting bacteria (PGPBs), reducing environmental impacts of N fertilizers and pesticides. We evaluate the effects of soybean inoculation with different bacterial consortia combined with PGPBs or microbial secondary metabolites (MSMs) on rhizosoil chemistry, plant physiology, plant nutrition, grain yield, and rhizosphere microbial functions under field conditions over three growing seasons with four treatments: standard inoculation of Bradyrhizobium japonicum and Bradyrhizobium diazoefficiens consortium (SI); SI plus foliar spraying with Bacillus subtilis (SI + Bs); SI plus foliar spraying with Azospirillum brasilense (SI + Az); and SI plus seed application of MSMs enriched in lipo-chitooligosaccharides extracted from B. diazoefficiens and Rhizobium tropici (SI + MSM).

View Article and Find Full Text PDF