Publications by authors named "O Chassin"
Article Synopsis
- Thrombolysis and endovascular thrombectomy (EVT) are standard stroke treatments, and this study investigates their effectiveness specifically in nonagenarians (patients aged 90 and older), hypothesizing that their prognosis may be worse than that of younger patients.
- The study analyzed outcomes of 96 nonagenarians treated with these therapies, finding that they had more pre-existing health conditions and lower independence before the stroke compared to patients aged 80-89.
- Results indicated that while treatment timelines and successful reperfusion rates were similar, nonagenarians had significantly poorer functional recovery at 3 months (14.3% vs. 34.0%) and a much higher mortality rate (60.2% compared to 16
Background: Hemorrhagic transformation (HT) is an uncommon complication of posterior circulation acute ischemic stroke (PCS) compared to anterior circulation stroke. Nevertheless, it remains a major concern especially following reperfusion therapy. This study aimed at identifying potential predictive factors associated with HT in PCS.
View Article and Find Full Text PDFExtending the stroke treatment window beyond DAWN in patients with very slow progressor type collaterals: How far can we go?
J Cerebrovasc Endovasc Neurosurg
December 2021
Five trials published in 2015 showed the benefit of endovascular thrombectomy (ET) in patients with stroke and large vessel occlusion, extending the treatment window has become an obsession of all physicians. In 2018, the DAWN and DEFUSE-3 trials showed that, with careful selection of patients, the procedure could be carried out up to 24 hours after symptom onset with good outcomes. In addition, there have been cases where the DAWN criteria were met, and treatment occurred >24 hours after symptom onset.
View Article and Find Full Text PDFBackground: While randomized clinical trials have shown the benefit of thrombolysis and endovascular thrombectomy (EVT) in patients with acute ischemic stroke (AIS), we aimed to describe in a real-life study the differences between older (>80 years old) and younger patients treated for AIS.
Methods: Thousand patients treated with thrombolysis and/or EVT were consecutively included in a prospective monocentric database (admitted from December 2015 to May 2019 in our comprehensive stroke center). Demographic data with detailed history, baseline physical examinations and treatments, laboratory and imaging data, prestroke functional status, and outcome 3 months after stroke were analyzed.