Publications by authors named "O Cannesson"
Article Synopsis
- The Modified vaccinia virus Ankara (MVA-BN) vaccine is recommended for individuals who have been exposed to mpox within 14 days, but its effectiveness remains uncertain.
- In a study of 108 adults who received the vaccine after exposure, 10% experienced breakthrough mpox infections.
- Sexual contact was identified as a significant risk factor for these breakthrough cases, and vaccinated individuals had similar rates of infectious virus presence compared to unvaccinated cases.
Article Synopsis
- Increasing cases of resistant cytomegalovirus infections in solid organ transplant recipients highlight the need for effective antiviral treatments like brincidofovir, which is designed to treat such infections without renal toxicity.
- This report shares two instances of severe tubular necrosis in a heart and kidney transplant patient after using brincidofovir, with no other contributing factors identified.
- The patients' renal function improved after stopping brincidofovir, suggesting a strong link between the drug and acute kidney injury, emphasizing the need for clinicians to monitor for this adverse effect in similar patients.
Background And Objectives: Infections caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) have become a major public health issue worldwide. Cefoxitin is a second-generation cephalosporin and is associated with a strong in vitro activity against ESBL.
Patients And Methods: We conducted a prospective monocentric cohort study from 2012 to 2015 to evaluate the clinical efficacy and safety of cefoxitin in 15 patients treated for urinary tract infection (UTI) caused by ESBL-E, without any severity criteria.