Publications by authors named "O C Kwok"
The development of inhibitory control (IC) and working memory (WM) in preschool is linked to a multitude of cognitive, emotional, and social outcomes, including elementary school adjustment. Furthermore, there are both cognitive and socioemotional domains of IC and it is unclear if both are related to these outcomes in the same manner. Using a family study design, the present investigation examined preschoolers' IC, WM and externalizing behavior problems, maternal depression and anxiety measured when the children were in preschool, and elementary school externalizing behaviors and child and family functioning.
View Article and Find Full Text PDFPoly(DL-lactide-co-glycolide) (PLGA) and N-methyl-2-pyrrolidone (NMP)-based in situ forming implants are liquid formulations that solidify through phase separation following injection into the body. Drug is dissolved or suspended in the final formulation liquid prior to injection. Depending on the polymers used, the depots formed can deliver drug over different periods of time.
View Article and Find Full Text PDFAge-related macular degeneration (AMD) is a degenerative eye disease leading to central vision loss and is characterized by dysregulated autophagy of the retinal pigment epithelium (RPE) layer. Recent studies have suggested that rho-associated protein kinase (ROCK) inhibitors may enhance autophagy in neurodegenerative diseases and promote the survival of RPE cells. This study investigated the effect of ROCK inhibitors on autophagy gene expression and autophagic vacuole formation in a human RPE (ARPE-19) cell line.
View Article and Find Full Text PDFHepatozoon sp. stages were detected in histological sections of the muscles of 11 of 25 bobcats (Lynx rufus). Parasites were detected from the myocardium of 11, tongues of 4, and limb muscles of 5 of these animals, which had been hunted in Mississippi in 2017.
View Article and Find Full Text PDFArticle Synopsis
- Environmental changes due to global warming are increasing the transmission of pathogens and parasites in Arctic wildlife, particularly polar bears, which serve as key indicators of these shifts.
- A study found that the prevalence of several pathogens in Chukchi Sea polar bears increased significantly between two time periods (1987-1994 and 2008-2017), although increased land use in summer by bears did not correlate with higher exposure levels.
- Female polar bears showed higher antibody prevalence for some pathogens, possibly linked to their terrestrial denning habits, and overall findings suggest a need for further research to monitor disease signs in polar bears, which are affected by climate change and serve as a food source for local communities.