Publications by authors named "O Bozdemir"
Article Synopsis
- - Perylene monoimide diesters and phenyl-linked bichromophores exhibit strong fluorescence in dilute solutions while generating very few triplet states post-excitation, indicating efficient energy relaxation.
- - The monomer in solution tends to form non-emissive face-to-face dimers, which upon illumination create a triplet pair with a yield of 13%, and this triplet has a short lifetime of about 80 ps before it decays.
- - When the concentration increases, self-association happens, especially with the -bridged bichromophore, resulting in reduced triplet formation in solvents like tetrahydrofuran at room temperature.
Non-melanoma skin cancer (NMSC) is one of the most prevalent cancers, leading to significant mortality rates due to limited treatment options and a lack of effective therapeutics. Janus kinase (JAK1), a non-receptor tyrosine kinase family member, is involved in various cellular processes, including differentiation, cell proliferation and survival, playing a crucial role in cancer progression. This study aims to provide a more effective treatment for NMSC by concurrently silencing the JAK1 gene and administering 5-Fluorouracil (5-FU) using liposome nanocomplexes as delivery vehicles.
View Article and Find Full Text PDFObjectives: The purpose of this study was to investigate the oxidative stress cycle consisting of reactive oxygen molecules (ROS), glutathione (GSH) and glutathione S-transferase (GST) in caries-related pulp inflammation.
Methodology: Fifty-four pulp tissue samples were collected from healthy donors with the diagnosis of reversible pulpitis, symptomatic irreversible pulpitis, and healthy pulp. Twelve pulp samples from each group were homogenized and total protein, ROS, GSH, and GST were measured by spectrophotometer.
Alzheimer's disease (AD) is a neurodegenerative disorder that causes memory loss and dementia and is characterized by a decline in cognitive functions. Brain infections, especially induced by herpes simplex virus type-1 (HSV-1), are suggested to play a key role in the pathogenesis of AD. Within the scope of this study, two different AD models (Tau model and amyloid beta [Aβ]) were created in the SH-SY5Y cell line, and HSV glycoprotein B (gB) was applied to the cell line and on the generated AD models.
View Article and Find Full Text PDFArticle Synopsis
- The mono-BF complex shows weak emission in fluid solution due to radiationless decay caused by an intramolecular hydrogen bond, while cracked symmetry leads to vibronic effects similar to the bis-BF complex (BOPHY).
- In single crystals, the complex exhibits 30% fluorescence quantum yield and 2 ns lifetime, with a significant Stokes shift (5,700 cm) reducing self-absorption.
- The crystal structure consists of head-to-tail molecular pairs that favor excitonic coupling; while standard methods overestimate the coupling strength, improved techniques provide accurate results, and temperature increases slightly shift the emission blue and reduce fluorescence.