Publications by authors named "O Bonnet"
Vent., an endemic plant from the Mascarene Islands, was investigated following its antiplasmodial potentialities highlighted during a previous screening. Three clerodane diterpene compounds were isolated and identified as being responsible for the antiplasmodial activity of the leaves of the plant: caseamembrin T (), corybulosin I (), and isocaseamembrin E (), which exhibited half maximal inhibitory concentrations (IC) of 0.
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- - Malaria continues to be a significant global health issue, worsened by the increasing resistance of the parasites to current treatments, prompting the search for new antimalarial options, particularly from plants known for their alkaloid content.
- - A study screened 43 methanolic extracts from 28 plant species, revealing 12 extracts with promising antiplasmodial activities, confirming previous findings and uncovering new potential treatments.
- - The use of advanced molecular networking techniques identified unknown alkaloids potentially effective against malaria, highlighting the importance of ongoing research into these plants for future drug development.
Introduction: Plants of the Strychnos genus, which include about 200 species, are used for multiple traditional purposes as hunting poison, for example, and have shown interesting pharmacological properties, especially curarizing and tetanizing, but also against malaria. Many monoterpene indole alkaloids have already been isolated and identified. Among them, there is strychnine, a famous alkaloid that can cause death by asphyxiation.
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- Determining herbage intake is essential for understanding grazing ecology, and this study compares the Continuous Bite Monitoring (CBM) method to the traditional double-weighing technique for measuring herbage intake in grazing sheep.
- The study involved various experiments that assessed factors affecting the reliability of CBM, such as observer count, forage species, and sward height, finding significant variations impacting intake estimations.
- Results showed a strong correlation between the two methods, but CBM tended to overestimate intake in certain experiments, highlighting its potential for detailed insights into foraging behavior while remaining non-invasive to animal activity.