Feasibility study of using next-generation reservoir computing (NG-RC) model to estimate liver tumor motion from external breathing signals.

Background: Respiratory motion is a challenge for accurate radiotherapy that may be mitigated by real-time tracking. Commercial tracking systems utilize a hybrid external-internal correlation model (ECM), integrating continuous external breathing monitoring with sparse X-ray imaging of the internal tumor position.

Purpose: This study investigates the feasibility of using the next generation reservoir computing (NG-RC) model as a hybrid ECM to transform measured external motions into estimated 3D internal motions.

Metastasis-directed stereotactic radiotherapy in patients with breast cancer: results of an international multicenter cohort study.

Metastasis-directed therapy (MDT) for oligometastatic breast cancer (≤ 5 metastases) has shown little effect in specific scenarios of randomized trials. Therefore, we aimed to assess outcomes after metastasis-directed stereotactic radiotherapy (SRT) in various clinical scenarios. We conducted an international retrospective cohort study in thirteen centers including breast cancer patients receiving SRT to any metastatic site.

Auto-contouring of cardiac substructures for Stereotactic arrhythmia radioablation (STAR): A STOPSTORM.eu consortium study.

Background/purpose: High doses to healthy cardiac substructures (CS) in stereotactic arrhythmia radioablation (STAR) raise concerns regarding potential treatment-induced cardio-toxicity. However, CS contours are not routinely created, hindering the understanding of the CS dose-effect relationships. To address this issue, the alignment of CS contouring was initiated within the STOPSTORM consortium.